Rapid Identification of Respiratory Tract Infections

Respiratory Tract Infections (RTIs) cause millions of deaths each year in adults and children worldwide. RTIs are difficult to diagnose rapidly and accurately leading to empirical treatment, misuse of antibiotics and increased patient morbidity and mortality.

Respiratory Tract Infections (RTIs) are caused by a variety of bacterial, viral, fungal and other pathogens. RTIs are major causes of morbidity and mortality in adults and children worldwide causing millions of deaths each year.

  • Current standard microbiological culture based tests are laborious and time consuming (> 30 hours to result) – patients initially treated empirically with antibiotics – inappropriate use of antibiotics – increase in patient morbidity and mortality
  • Urgent need for rapid molecular diagnostics tests capable of identifying a large range of microorganisms and antibiotic resistances. 

The aims of the RiD-RTI project are to develop and evaluate three diagnostics products for the rapid diagnosis of:

  1. Community acquired pneumonia
  2. Hospital acquired/ventilator associated pneumonia
  3. Opportunistic respiratory tract infections

The products will be developed on a novel “sample-in, answer-out” diagnostic platform for the rapid (< 2 hrs) and accurate detection, identification and molecular drug susceptibility testing of RTIs.